Radium uses1/7/2024 There are also beta and gamma emissions with different energies and emission probabilities. The six-stage-decay of radium-223 to stable lead-207 occurs via short-lived daughters, and is accompanied predominantly by alpha emissions. The specific activity of radium-223 is 1.9 MBq (51.4 microcurie)/ng. The molecular weight of radium-223 dichloride, 223RaCl 2, is 293.9 g/mol. The inactive ingredients are 6.3 mg/mL sodium chloride USP (tonicity agent), 7.2 mg/mL sodium citrate USP (for pH adjustment), 0.2 mg/mL hydrochloric acid USP (for pH adjustment), and water for injection USP. Radium is present in the solution as a free divalent cation.Įach vial contains 6 mL of solution (6,600 kBq (178 microcurie) radium-223 dichloride at the reference date). Xofigo is supplied as a clear, colorless, isotonic, and sterile solution to be administered intravenously with pH between 6 and 8.Įach milliliter of solution contains 1,100 kBq radium-223 dichloride (30 microcurie), corresponding to 0.58 ng radium-223, at the reference date. Radium Ra 223 dichloride, an alpha particle-emitting pharmaceutical, is a radiotherapeutic drug. You may report side effects to FDA at 1-80. For more information, ask your doctor or pharmacist.Ĭall your doctor for medical advice about side effects. These are not all the possible side effects of Xofigo. Tell the doctor if you have any side effect that bothers you or that does not go away. The most common side effects of Xofigo include: Get medical help right away, if you have any of the symptoms listed above. swelling of your face, lips, tongue, or throat,.Xofigo may cause serious side effects including: What are the possible side effects of Xofigo? It is not known if Xofigo is safe and effective in children. Xofigo belongs to a class of drugs called Radiopharmaceuticals. Xofigo may be used alone or with other medications. Xofigo is a prescription medicine used to treat the symptoms of Prostate Cancer.
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